From Tel Aviv Bus Station
If you’re in Tel Aviv city, then head over to the bus station and catch one of the many sheruts waiting to pick up passengers.
The sherut ride takes about 45 minutes to reach the center of Jerusalem on Jaffa Rd. Make sure to inform the driver of the address you are heading to, so that you can get down at the appropriate and closest location. Most sherut drivers pass through the main street – Jaffa road, but unless you want to be dropped in the middle of nowhere, make sure to check with the drop-off place with the driver.
Private taxis are about NIS 300 (about $80).
Jerusalem’s new train station is located in southwest of the city, near the Jerusalem mall. Trains to Tel Aviv’s Arlosoroff station (adult/child NIS 25/20) depart hourly between 06:10 to 21:10, Sunday to Thursday. The station can be reached on bus no. 6 from Jaffa Road or the central bus station.
The more scenic train ride (NIS 22/ $6) threads through the hills to Jerusalem Malha station. Take a train to Tel Aviv HaHagana station and change (rail.co.il). It takes two hours & 15 minutes.
The City Centre and the Jewish Quarter of the Old City are closed on Friday after sunset and Saturday, when people observe Shabbat, but this is just another day for Jerusalem’s Arab population, and most of the sights are open in the Old City, Mt Zion, the Mount of Olives and East Jerusalem.