Copyright 2012 by Dr. Shahzad Waseem
Drugs used in ophthalmology
Topical medicines when instilled in the eye enter the anterior chamber of the eye through cornea.
Their effects are limited to the anterior chamber & anterior segment of the eye
Penetration of drugs depends upon their lipid solubility.
There are two blood-ocular barriers.
1. Blood aqueous barrier. It is formed by the non-pigmented ciliary epithelium and endothelium of the iris blood vessels.
2. Blood-retinal barrier
Types of topical administration