This book has a refreshing new take on relationships. It will require the reader to 'think outside the box' of societal expectations of gender specific roles in society. And also to allow themselves to be willing to experience new ways of relating which I have found to actually work. I found it useful in understanding the challenges in relationships I have or had with work colleagues, family members, friends as well as lovers. The Four Genders Handbook cannot really be compared to any other book I have read on relationships because of its unique stance on relationship dynamics, but I do think that it has the potential to impact relationships in the 21st century as 'Men Are from Mars, Women Are from Venus' did in the 1990s.